LIED (UMR 8236) – Laboratoire Interdisciplinaire des Énergies de Demain

Recombination suppression often evolves around sex-determining loci and extends stepwise, resulting in adjacent regions with different levels of divergence between sex chromosomes, called evolutionary strata. In Ascomycota fungi, evolutionary strata around the mating-type (MAT) locus have been […]

Cryptophycins are a group of cyclodepsipeptides that are among the most potent anti-proliferative agents ever described. The parent compound, cryptophycin-1 was isolated from two Nostoc cyanobacterial strains (ATCC 53789 and GSV224), and it binds tightly to tubulin, inhibits microtubule […]

Much of today's sustainability discourse emphasizes efficiency, clean technologies, and smart systems, but largely underestimates fundamental physical constraints relating to energy-matter interactions. These constraints stem from the fact that Earth is a materially closed yet energetically open […]

Proprioception is the integrated sense of self-movement and body position in complex organisms. Here we describe a novel, mechanical form of proprioception driving directional choice making in tip-growing helical organisms. We show that C. albicans hyphae utilize their built-in helicity as an […]

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Balancing economic and resource constraints in the deployment of energy transition technologies

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Abstract The laterodorsal tegmentum (LDT) sends critical inputs to distinct reward circuit regions, including the nucleus accumbens (NAc), but their functional role in addiction-related behaviors remains underexplored. Here, we demonstrate that LDT-NAc cholinergic projections undergo […]

Outdoor air temperature measurements are essential to be applied to agriculture, meteorology, hydrology, and urban planning. Precise measurements are particularly needed in the lower troposphere where the existence of large temperature gradients is prevalent. Urban temperature observation has been […]