{"id":45113,"date":"2026-07-20T15:06:03","date_gmt":"2026-07-20T13:06:03","guid":{"rendered":"https:\/\/u-paris.fr\/sante\/?p=45113"},"modified":"2026-07-20T15:13:58","modified_gmt":"2026-07-20T13:13:58","slug":"keynote-recherche-guillaume-canaud-la-medecine-translationnelle-au-service-des-maladies-rares-de-la-decouverte-au-traitement","status":"publish","type":"post","link":"https:\/\/u-paris.fr\/sante\/keynote-recherche-guillaume-canaud-la-medecine-translationnelle-au-service-des-maladies-rares-de-la-decouverte-au-traitement\/","title":{"rendered":"[Keynote Recherche] Guillaume Canaud : La m\u00e9decine translationnelle au service des maladies rares : de la d\u00e9couverte au traitement"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00a0\u00bb1&Prime; _builder_version=\u00a0\u00bb3.22&Prime;][et_pb_row _builder_version=\u00a0\u00bb3.22&Prime; background_size=\u00a0\u00bbinitial\u00a0\u00bb background_position=\u00a0\u00bbtop_left\u00a0\u00bb background_repeat=\u00a0\u00bbrepeat\u00a0\u00bb][et_pb_column type=\u00a0\u00bb3_4&Prime; _builder_version=\u00a0\u00bb3.0.47&Prime;][et_pb_text admin_label=\u00a0\u00bbIntro\u00a0\u00bb module_id=\u00a0\u00bbintro\u00a0\u00bb _builder_version=\u00a0\u00bb3.22.1&Prime;]<\/p>\n<p><strong>From a single patient to an US FDA approved drug \u2013 the story of a drug repositioning for a rare disease.<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><em>Le Pr <strong>Guillaume Canaud<\/strong> est n\u00e9phrologue \u00e0 l&rsquo;H\u00f4pital Necker \u2013 Enfants Malades, professeur \u00e0 l&rsquo;Universit\u00e9 Paris Cit\u00e9 et chercheur \u00e0 l&rsquo;Inserm. Ayant plus de 100 publications \u00e0 son actif, il a \u00e9t\u00e9 r\u00e9compens\u00e9 par de nombreux prix pour ses d\u00e9couvertes (dont le Prix de l&rsquo;Innovation Inserm 2024 et le Prix Galien) et a d\u00e9pos\u00e9 plus de 15 brevets. Il est aujourd&rsquo;hui une r\u00e9f\u00e9rence internationale en m\u00e9decine translationnelle, qui fait le lien entre la recherche en laboratoire et les soins apport\u00e9s aux patients.<\/em><\/p>\n<p>&nbsp;<\/p>\n<p>Dans cette pr\u00e9sentation en fran\u00e7ais, Guillaume Canaud pr\u00e9sente les travaux de son \u00e9quipe sur les syndromes de surcroissance asym\u00e9triques et retrace l\u2019histoire profond\u00e9ment humaine d\u2019un m\u00e9dicament ayant permis de sauver un patient en 2015 dans le cadre sp\u00e9cifique d\u2019un essai acc\u00e8s compassionnel avec un m\u00e9dicament alors en cours de d\u00e9veloppement pour le cancer du sein, et depuis 2022 autoris\u00e9 par l\u2019autorit\u00e9 sanitaire am\u00e9ricaine dans cette nouvelle indication de syndrome de surcroissance gr\u00e2ce \u00e0 ses travaux, et enfin tr\u00e8s r\u00e9cemment par les autorit\u00e9s sanitaires europ\u00e9ennes.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_4&Prime; _builder_version=\u00a0\u00bb3.0.47&Prime;][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb3.22&Prime; background_size=\u00a0\u00bbinitial\u00a0\u00bb background_position=\u00a0\u00bbtop_left\u00a0\u00bb background_repeat=\u00a0\u00bbrepeat\u00a0\u00bb][et_pb_column type=\u00a0\u00bb3_4&Prime; _builder_version=\u00a0\u00bb3.0.47&Prime;][et_pb_text module_id=\u00a0\u00bbcontenu\u00a0\u00bb _builder_version=\u00a0\u00bb3.22.1&Prime;]<\/p>\n<p><iframe loading=\"lazy\" title=\"Keynote recherche - Guillaume Canaud, From a single patient to an US FDA approved drug...\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/7fgf6Gt05C0?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_4&Prime; _builder_version=\u00a0\u00bb3.0.47&Prime;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1&Prime; _builder_version=\u00a0\u00bb3.22&Prime; custom_padding=\u00a0\u00bb0px||0px|\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb3.22&Prime;][et_pb_column type=\u00a0\u00bb4_4&Prime; _builder_version=\u00a0\u00bb3.0.47&Prime;][et_pb_text admin_label=\u00a0\u00bb\u00c0 lire aussi\u00a0\u00bb _builder_version=\u00a0\u00bb3.22.1&Prime;]<\/p>\n<h2><span class=\"st\">\u00c0<\/span> lire aussi<\/h2>\n<p>[\/et_pb_text][et_pb_blog posts_number=\u00a0\u00bb4&Prime; include_categories=\u00a0\u00bb1,61,17&Prime; show_author=\u00a0\u00bboff\u00a0\u00bb show_date=\u00a0\u00bboff\u00a0\u00bb show_pagination=\u00a0\u00bboff\u00a0\u00bb module_id=\u00a0\u00bbpage_type_blog\u00a0\u00bb _builder_version=\u00a0\u00bb3.22.1&Prime; header_level=\u00a0\u00bbh4&Prime; border_width_bottom_fullwidth=\u00a0\u00bb1px\u00a0\u00bb border_color_bottom_fullwidth=\u00a0\u00bbrgba(51,51,51,0.18)\u00a0\u00bb custom_padding=\u00a0\u00bb||50px|\u00a0\u00bb][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>From a single patient to an US FDA approved drug \u2013 the story of a drug repositioning for a rare disease. &nbsp; Le Pr Guillaume Canaud est n\u00e9phrologue \u00e0 l&rsquo;H\u00f4pital Necker \u2013 Enfants Malades, professeur \u00e0 l&rsquo;Universit\u00e9 Paris Cit\u00e9 et chercheur \u00e0 l&rsquo;Inserm. Ayant plus de 100 publications \u00e0 son actif, il a \u00e9t\u00e9 r\u00e9compens\u00e9&hellip; <a class=\"continue\" href=\"https:\/\/u-paris.fr\/sante\/keynote-recherche-guillaume-canaud-la-medecine-translationnelle-au-service-des-maladies-rares-de-la-decouverte-au-traitement\/\">Lire la suite<span> [Keynote Recherche] Guillaume Canaud : La m\u00e9decine translationnelle au service des maladies rares : de la d\u00e9couverte au traitement<\/span><\/a><\/p>\n","protected":false},"author":731,"featured_media":45134,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[1,61,17],"tags":[],"coauthors":[79],"class_list":["post-45113","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculte-de-sante","category-keynotes-fr","category-recherche"],"_links":{"self":[{"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/posts\/45113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/users\/731"}],"replies":[{"embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/comments?post=45113"}],"version-history":[{"count":6,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/posts\/45113\/revisions"}],"predecessor-version":[{"id":45133,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/posts\/45113\/revisions\/45133"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/media\/45134"}],"wp:attachment":[{"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/media?parent=45113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/categories?post=45113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/tags?post=45113"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/u-paris.fr\/sante\/wp-json\/wp\/v2\/coauthors?post=45113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}